Characteristics of neonatal Covid-19 in Turkey

The investigators aimed to investigate the clinical and epidemiological characteristics of neonates who will be born to Covid-19 positive mothers in Turkey. It is a multicentric prospective cohort study designed and destined only in Turkey. The investigators are planning to admit more than 20 Neonatal Intensive Care Units into the survey; nevertheless, the total number may change according to the prevalence of Covid-19 in neonates.

The investigators will also inquire into vertical transmission by collecting cord blood, placental, and postnatal serum samples to test for Covid-19 PCR and Covid-19 Ig M and IgG values from the neonates.

Observational Prospective Cohort

Biospecimen Retention:   Samples With DNA
Nasopharyngeal, endotracheal aspirates of the neonate for Covid-19 Placenta and blood and stool samples of the neonate Milk of the mother

Primary Outcome Measures  :

• Vertical Transmission [ Time Frame: First 28 days of life ]
• Vertical transmission will be investigated by obtaining neonatal PCR samples in blood, stool and mother milk as well as Neonatal Covid-19 Ig M and Ig G values

Secondary Outcome Measures  :

• Hospital stay [ Time Frame: First 28 days of life ]
• Hospital span time of the neonates in NICU
• Early neonatal sepsis rate [ Time Frame: First 3 days ]
• Early neonatal sepsis rate

Clinical Trials Identifier NCT04401540

Epidemiology
Vulnerable Populations

May 2020 — Oct 2020

Türkiye

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