Assessing the contribution of migration to the emergence and spread of antimalarial drug resistance in Bangladesh

Objectives

The overall goal is to use rigorous methods for combining clinical, genomic, and mobile phone data to determine the role of population movement on the distribution and spread of malaria and artemisinin resistance in Southeast Bangladesh.

This proposal will allow the development of appropriate analytical methods and the application of them to pilot data from a high risk but relatively under-studied region in order to:

• confirm the emergence of artemsinin resistance in these populations,
• establish a proof of principle for this approach and strong collaborative ties with local researchers, and
• produce preliminary data that will form the basis of a larger R01 (or equivalent) proposal.