Last Updated: 27/06/2024

Cheap drugs for bad bugs: engineering natural product synthesis

Objectives

The project team sought to develop prototype systems for the production of complex natural products in metabolically simple hosts (like E. coli). By engineering bacteria, this project aims to produce natural, low-cost drugs for the developing world. 

Principal Investigators / Focal Persons

Katherine Ryan

Rationale and Abstract

The developing world faces parasitic diseases (such as leichmaniasis and malaria) with limited tools for treatment. For-profit pharmaceutical companies rarely invest in the development of drugs for such diseases, because it is not economic to do so. Natural products are one possible source of new pharmaceuticals.

Date

Mar 2014 — Sep 2015

Project Site

India

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