An active malaria epidemiology cohort study in personnel and dependents of the Royal Cambodian Armed Forces with evaluation of a 2 day versus 3 day treatment regimen of DHA-Piperaquine for patients with uncomplicated malaria.

Objectives

1. To evaluate malaria attack rates in a cohort of healthy military personnel.    
2. To compare treatment with 2 vs. 3 day regimens of DHA-piperaquine for those developing malaria during the study.

This study is the first step in determining the feasibility of conducting future malaria prophylaxis studies at this site, and characterizing the population, malaria epidemiology and effectiveness of currently prescribed anti-malarial therapy with 2 days of DHA-piperaquine.