Last Updated: 23/02/2024

Study of the genetic diversity of P.vivax and P. falciparum in various malaria endemic settings in Bangka and Sumba islands, Indonesia

Objectives

To investigate molecular approaches to inform the respective transmission dynamics of P. falciparum and P. vivax and how these could help to prioritize public health interventions.

Specific objectives:

  • To study the genetic diversity and population structure of P. vivax in various malaria endemic settings in Indonesia to assess whether infection in these two islands originate from a common reservoir
  • To determine the allelic frequencies of P. vivax between different populations

  • To develop a robust technique for allelic determination applicable for field studies
Principal Investigators / Focal Persons

Rintis Noviyanti

Rationale and Abstract

Outside of Africa, P. falciparum and P. vivax usually coexist. In such co-endemic regions, successful malaria control programs have a greater impact on reducing falciparum malaria, resulting in P. vivax becoming the predominant species of infection. Adding to the challenges of elimination, the dormant liver stage complicates efforts to monitor the impact of ongoing interventions against P. vivax

Date

Sep 2011 — Jul 2013

Total Project Funding

$52,349

Project Site

Indonesia

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