Evaluating re-active surveillance strategies for malaria elimination in Swaziland
The specific objectives of this project are to:
- Compare pooled PCR to rapid diagnostic test (RDT) for improved detection of secondary malaria infections,
- Identify epidemiological factors associated with the detection of secondary infections in re-active surveillance, and
- Build and test a model for predicting the location of hot spots utilizing RDT, PCR, epidemiological data, and malaria serology.
The global burden of disease caused by malaria is tremendous. The proposed research program will take place in Swaziland, a country in southern Africa endeavouring to eliminate malaria, and will critically evaluate re-active surveillance, a strategy whereby the communities of known malaria cases are screened as a way to identify other cases and hot spots. The results will help to focus future research and malaria interventions in Swaziland and many other countries aiming to eliminate malaria.