Last Updated: 01/09/2025

Evaluating the impact of larviciding with Bti and community education and mobilization as supplementary integrated vector management interventions for malaria control in Kenya and Ethiopia

Objectives

To assess the effect of supplementing LLINs with either larviciding with Bacillus thuringiensis israelensis (Bti) or community education and mobilization (CEM), or with both interventions in the context of integrated vector management (IVM).

The study specifically aimed at verifying under field conditions if adding larviciding and CEM either individually or combined can further reduce indoor malaria vector density and malaria prevalence in the community compared to when LLINs alone are used.

Principal Investigators / Focal Persons

Charles M Mbogo

Rationale and Abstract

Malaria prevention in Africa is mainly through the use of long-lasting insecticide treated nets (LLINs). The objective of the study was to assess the effect of supplementing LLINs with either larviciding with Bacillus thuringiensis israelensis (Bti) or community education and mobilization (CEM), or with both interventions in the context of integrated vector management (IVM).

Study Design

Factorial, cluster-randomized, controlled trial. In each site there were 16 villages (clusters), with four villages randomly assigned to each of the four study arms: LLINs only (arm 1); LLINs and Bti (arm 2); LLINs and CEM (arm 3); and, LLINs combined with Bti and CEM (arm 4).

 

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