Last Updated

06 May 2020

Unitaid Calls For Proposals: Intermittent Preventive Treatment in infants

Under this Call, Unitaid is soliciting proposals for the following interventions, aimed at accelerating the adoption and scale-up of Intermittent Preventive Treatment in infants (IPTi) in moderate-to-high transmission settings:

Implementation pilots for IPTi delivery to catalyse country uptake and inform future policy and guidelines. 

Projects can include:

  • Proof-of-concept pilots that demonstrate the impact, operational feasibility and cost-effectiveness of at-scale IPTi delivery
  • Evaluation of modifications to the current IPTi schedule, particularly those that leverage additional vaccination contacts at ages where the risk of severe malaria disease and death are highest, potentially expanding IPTi coverage into the second year of life
  • Delivery of IPTi through alternative platforms that complement the existing EPI schedule which could help fill coverage gaps, such as nutrition or weigh-in visits, antenatal care contacts (when pregnant women present with infants), community delivery under the Integrated Community Case Management platform, or other opportunities
  • Sub-national approaches to IPTi implementation, particularly in countries that are implementing Seasonal Malaria Chemoprevention, but also have regions with less seasonal malaria transmission where children do not currently benefit from chemoprevention but could benefit from IPTi
  • Testing of IPTi in areas of medium-to-high malaria transmission, where levels of parasite resistance are above the WHO recommended threshold of 50% (e.g. in certain regions of East Africa), to determine the resistance thresholds under which IPTi remains effective

Proposals can address one or more of the items above. Proposals should demonstrate plans for close engagement with national immunization programmes. Proposals should also recognize that challenges related to the adoption of IPTi can be closely related, and should therefore reflect the proponent’s ability to coordinate closely with other actors in this space.

Proposals deadline March 11, 2020 (12:00 noon Central European Time).

Read more and apply here

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