Studies to demonstrate the feasibility of the use of the malaria LAMP kit for population screening in Zanzibar
Loop-mediated isothermal amplification (LAMP) is a simplified DNA amplification technique that combines the highly-sensitive property of molecular diagnostic tools with minimal laboratory infrastructure requirements.
The overall objective of this project is to demonstrate the feasibility of malaria LAMP kit for identifying asymptomatic cases.
Asymptomatic, low parasite density malaria infections are difficult to detect with currently available point-of-care diagnostics. This study piloted a loop-mediated isothermal amplification (LAMP) kit for field-friendly, high-throughput detection of asymptomatic malaria infections during mass screening and treatment (MSAT) in Zanzibar, a malaria pre-elimination setting.