Last Updated

20 Nov 2020

Preventive malaria treatment among school-age children in sub-Saharan Africa: a systematic review and meta-analysis

Objectives
  1. Does antimalarial treatment of asymptomatic school-age children decrease the prevalence of malaria infection compared with placebo or no treatment?
  2. Does antimalarial treatment of asymptomatic school-age children decrease the prevalence of anemia compared with placebo or no treatment?
  3. Does malaria transmission intensity explain variation in the protective effect of antimalarial treatment among asymptomatic school-age children against malaria infection and/or anemia?
Principal Investigator
Rationale and Abstract

Multiple studies have shown high prevalence of malaria, largely “asymptomatic”, in school-age children in sub-Saharan Africa. Studies assessing the impact of treating asymptomatic school-age children either in schools or in communities have had mixed results. It is not clear if this variation is due to the details of the interventions or the transmission intensity of the study site.

Study Design

Systematic Review, Study-level meta-analysis, Individual participant data meta-analysis