Last Updated

28 Sep 2020

Population parasite clearance to decrease malaria transmission in Amhara Region, Ethiopia: a pilot study


To evaluate whether different parasitaemia clearing strategies can decrease malaria transmission and provide necessary information on demographic and spatial patterns of infection to guide the strategy towards elimination in very low to moderate transmission areas in Amhara region.

Principal Institution(s)

Principal Investigator
Rationale and Abstract

Intervention kebeles were selected based on incidence of passively detected Plasmodium falciparum and mixed (P. falciparum and P. vivax) malaria cases during the 2013 malaria transmission season. All households in intervention kebeles were targeted; consenting residents received a rapid diagnostic test (RDT) and RDT-positive individuals received artemether-lumefantrine for P. falciparum/mixed infections or chloroquine for P. vivax. Data were collected on MTAT participation, sociodemographic characteristics, malaria risk factors, and RDT positivity.

The primary outcome measured is the malaria infection prevalence as measured by RDTs.

Six kebeles (villages) were purposively selected from a sample of 209 kebeles in eight districts in Amhara Region, Ethiopia, that collectively span the diverse ecological-epidemiological context across the region. Each of these kebeles is served by a health post.


2014 Jan - 2015 Dec

Funding Details

Core funding, OPP1089412
Project Site