Mentoring and patient-oriented research in malaria
This project includes an integrated, comprehensive mentoring plan to train U.S.- and Malawi-based investigators in the technical, scientific and professional skills required to succeed in patient-oriented research. The applicant and her research team strive to design hypothesis-driven studies that lead to evidence-based interventions to improve the health of those who suffer from malaria and contribute scientific insight to help eradicate malaria.
The specific research aims of this proposal focus on interventions to prevent malaria in two vulnerable populations: pregnant women and their babies, in whom the malaria risk is well known but for whom preventive strategies are inadequate, and school-age children, a population newly recognized to suffer from high rates of malaria infection.
Despite remarkable advances in our understanding of the biology of malaria over the last 30 years, malaria elimination remains elusive in Malawi, among other sub-Saharan African countries. The applicant has focused her academic career on using genetics and epidemiology to address key public health questions related to treating and preventing malaria, and to training U.S. - and Malawi-based investigators to conduct patient-oriented malaria research to this end.