Intermittent preventive treatment for malaria among children in a refugee camp in Northern Uganda
To implement intermittent preventive treatment for malaria (IPTc, MDA in children) in two refugee camps among children aged 6 months to 14 years, document the effects of the intervention on malaria incidence and prevalence and document side effects potentially related to repeated doses of DP.
Northern Uganda hosts a large population of refugees from South Sudan, and malaria is one of the major health problems in the area. In 2015, intermittent preventive treatment for malaria (IPTc) was implemented in two refugee camps among children aged 6 months to 14 years. Three distributions of dihydroartemisinin–piperaquine (DP) were conducted at 8-week intervals.
The study population consisted of the entire refugee population of Ayilo 1 (area: 3.8 sq km) and Ayilo 2 (area: 2.4 sq km) camps, a total population of 29,855 refugees as well as the members of their host community, population approximately 1000 persons).
- Drug & regimen: 3 rounds of dihydroartemisinin-piperaquine were administered at 8-week intervals at specific distribution sites. The first dose was directly administered at IPTc distribution sites and the second and third doses were given to caregivers to administer at home.
- Concomitant interventions: Reinforced surveillance, pharmacovigilance and LLINs distribution upon arrival to camps.
- Target & size population: Refugee population of Ayilo 1 (area: 3.8 sq km) and Ayilo 2 (area: 2.4 sq km) camps, 40,611 children received DP
- Inclusion criteria: Children aged 6 months to 14 years