Genetic structuring, susceptibility to insecticides and contribution of Anopheles melas to residual malaria transmission in Senegal.

The overall aim of this study is to evaluate the entomological factors favouring the persistence of malaria transmission in hot spots in Senegal and to evaluate the contribution of An. melas in the residual transmission.

Specific objectives:

1.To estimate the population dynamics of An. melas and its contribution to residual malaria transmission in Senegal.
2.To characterize An. melas breeding sites in the studied villages and identify the relationship between breeding site location and density and house infestation.
3.To evaluate the susceptibility of An. melas populations to insecticides and identify the potential mechanisms involved. 
4.To determine the genetic structure of An. melas populations in Senegal and the potential genetic exchanges with the other members of the An. gambiae complex.