Last Updated

22 Oct 2020

Evaluation of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence

Objectives

Rising insecticide resistance and increased outdoor transmission have greatly hampered the effectiveness of insecticide-treated nets (ITN) and indoor residual spraying (IRS) because the current indoor-based interventions do not target the outdoor-biting mosquitoes. Therefore, new supplemental interventions that can tackle outdoor transmission and pyrethroid insecticide resistance are urgently needed.

The central objective of this study is to determine the efficacy and cost-effectiveness of EPA-approved long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence in western Kenya highlands.

Principal Institution(s)

Principal Investigator
Rationale and Abstract

ClinicalTrials.gov Identifier: NCT02392832

Study Design
Study Type  : Interventional  (Clinical Trial)
Actual Enrollment  : 240000 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)