Evaluation of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence
Rising insecticide resistance and increased outdoor transmission have greatly hampered the effectiveness of insecticide-treated nets (ITN) and indoor residual spraying (IRS) because the current indoor-based interventions do not target the outdoor-biting mosquitoes. Therefore, new supplemental interventions that can tackle outdoor transmission and pyrethroid insecticide resistance are urgently needed.
The central objective of this study is to determine the efficacy and cost-effectiveness of EPA-approved long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence in western Kenya highlands.
ClinicalTrials.gov Identifier: NCT02392832
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||240000 participants|
|Intervention Model:||Crossover Assignment|